Impact of Extranodal Extension in Patients With Regional Metastases of Head and Neck Cutaneous Squamous Cell Carcinoma. | Synapse
March 7, 2026
Impact of Extranodal Extension in Patients With Regional Metastases of Head and Neck Cutaneous Squamous Cell Carcinoma.
Key Points
The research aims to evaluate the role of extranodal extension in head and neck cutaneous squamous cell carcinoma with regional metastases.
Analysis of cases with head and neck cutaneous squamous cell carcinoma
Assessment of extranodal extension prevalence
Evaluation of current nodal staging criteria
Extranodal extension is commonly found in metastatic cases
It does not provide independent prognostic information
Current nodal staging methods are inadequate for HNcSCC.
Abstract
pENE is highly prevalent in metastatic HNcSCC but lacks independent prognostic significance. More discriminatory, HNcSCC-specific nodal staging criteria are needed.