Following the 2023 extension of HPV vaccine eligibility (9–45 years) in China, public demand for HPV-related health information has surged, with Bilibili (a long-form knowledge platform) and TikTok (a short-form high-engagement platform) emerging as core sources. This study aimed to compare uploader characteristics, content features, information quality, and the correlation between audience engagement and quality of HPV-related videos on the two platforms. On August 8, 2025, we retrieved the top 100 videos from each platform using three search terms: “HPV vaccine”, “human papillomavirus infection”, and “cervical cancer screening”. Prior to retrieval, user accounts were logged out and browsing histories cleared to avoid personalized recommendation biases, with results displayed in the platforms’ default comprehensive ranking. After excluding irrelevant, duplicate, silent, and advertisement videos (as well as those published 0.05). TikTok serves as an effective channel for introductory HPV science communication, while Bilibili is better suited for systematic knowledge acquisition. To enhance public health impact, platforms, creators, and regulators should collaborate: TikTok should establish quality thresholds for short-form health content, and Bilibili should further enhance the depth of professional HPV content.
Jiang et al. (Sun,) studied this question.