What does this research mean for the field?

Systemic administration of Bifidobacterium animalis subsp. lactis HN019 or its derived postbiotic does not improve periodontal outcomes in rats with induced periodontitis. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the effects of live and heat-killed Bifidobacterium lactis on periodontal health in a rat model of induced periodontitis.

March 13, 2026Open Access

Effects of live and heat-killed Bifidobacterium lactis in rats with induced periodontitis

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Key Points

To evaluate the effects of live and heat-killed Bifidobacterium lactis on periodontal health in a rat model of induced periodontitis.
Administered Bifidobacterium animalis subsp. lactis HN019 and its postbiotic to rats
Induced periodontitis in rat subjects
Measured periodontal health outcomes
Compared effects between live and heat-killed forms.
No significant improvements in periodontal outcomes were observed
Findings suggest limited systemic effects of the tested probiotics and postbiotics

Abstract

Systemic administration of Bifidobacterium animalis subsp. lactis HN019 or its derived postbiotic resulted in no significant improvements in periodontal outcomes in this experimental model. Further investigations using integrative approaches are needed to better characterize the systemic effects of probiotics and postbiotics.

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Authors

Tainá da Silva TRICOLY

Universidade Estadual Paulista (Unesp)

Thaís Aguiar Santos

Universidade do Estado de Mato Grosso

Camila Lopes Ferreira

Universidade Estadual de Ponta Grossa

Journals

Journal of Applied Oral Science

SHILAP Revista de lepidopterología

Actions

Institutions

Universidade Estadual Paulista (Unesp)

Universidade de Taubaté

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Effects of live and heat-killed Bifidobacterium lactis in rats with induced periodontitis

Key Points

Abstract

Citation Network

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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