Elucidation and applicaiton of the metabolic regulatory network across developmental stages in lettuce

Key Points

• The research aims to explore the metabolic regulatory network in lettuce throughout its developmental stages.
• Constructed multi-omics atlas covering the entire growth period of lettuce
• Identified regulatory modules related to light-dependent flavonoid biosynthesis
• Investigated transcription factor and target gene colocalization in sesquiterpene lactone synthesis
• Characterized functional differentiation of SCPL acyltransferase in chicoric acid synthesis
• Discovered the regulatory module LsBBX20-LsMYB114 for flavonoid biosynthesis
• Revealed a cooperative regulatory mechanism involving transcription factor LsERF166
• Identified key genes crucial for improving nutritional quality in lettuce