The SAG101–NRG1 branch of TIR signaling activates phenylalanine‐derived SA biosynthesis in Nicotiana benthamiana

Key Points

• This research aims to understand how Nicotiana benthamiana differs from Arabidopsis in activating salicylic acid biosynthesis through TIR signaling.
• Examined the SAG101-NRG1 pathway of TIR signaling in Nicotiana benthamiana
• Analyzed salicylic acid biosynthesis activation
• Compared signaling mechanisms between Nicotiana benthamiana and Arabidopsis
• Identified the SAG101–NRG1 branch as key in activating salicylic acid production
• Demonstrated evolutionary differences in immune signaling between plants
• Revealed that both species utilize different mechanisms to control salicylic acid biosynthesis.