Porous organic polymers based on deep-cavity calixarene for broad-spectrum and high-affinity drug adsorption in gastrointestinal tract

Key Points

• The aim is to explore the use of porous organic polymers based on deep-cavity calixarene for enhancing drug adsorption in the gastrointestinal tract.
• Synthesis of porous organic polymers using calixarene.
• Evaluation of drug adsorption capacity through laboratory experiments.
• Analysis of adsorption efficiency under various gastrointestinal conditions.
• Demonstrated high-affinity drug adsorption with the calixarene-based polymers.
• Showed effective mitigation of local side effects from drugs in the digestive tract.
• Indicated potential for immediate intervention in drug overdose situations.