Development and Validation of a Continuous Real‐Time Optical Sensor for Indocyanine Green Clearance Measurement During Ex Vivo Perfusion of Human Livers

Key Points

• The aim is to develop a reliable optical sensor for continuous monitoring of indocyanine green (ICG) clearance during liver perfusion.
• Development of a real-time optical sensor.
• Validation of the sensor in an ex vivo perfusion setting.
• Assessment of ICG clearance models for clinical application.
• The sensor demonstrates accurate real-time monitoring of ICG clearance.
• Enhanced clinical interpretation was observed during perfusion.
• Supports informed decision-making regarding liver graft assessment.