Osteosarcoma is not a single disease: Considerations for multidisciplinary management of jaw (gnathic) osteosarcoma

Key Points

• This research aims to differentiate gnathic osteosarcoma from other types and improve management strategies.
• Review of existing literature on gnathic and appendicular osteosarcoma
• Development of consensus guidelines based on findings
• Identification of key recommendations for treatment
• Gnathic osteosarcoma shows different responses to systemic therapies compared to appendicular osteosarcoma.
• Guidelines suggest focusing on specific subtypes to enhance treatment outcomes.
• Consensus recommendations may guide future research directions in osteosarcoma management.