ABSTRACT A simple phenylhydrazine‐based colorimetric chemosensor, AN04 , was synthesized using 4‐(diethylamino)benzaldehyde and (2,4‐dinitrophenyl)hydrazine in ethanol, yielding a highly efficient and selective probe for cyanide (CN − ) detection. The probe exhibits a distinct color change from yellow to pink upon interaction with cyanide ions in acetonitrile medium, enabling both naked‐eye and UV‐Vis spectrophotometric detection. AN04 exhibits high selectivity and sensitivity towards CN − over other common anions, with a significant redshift in absorbance from 434 nm to 487 nm. Job's plot confirmed a 1:1 binding stoichiometry, with a detection limit of 9.7 × 10 − 8 M and binding constant 1.27 × 10 5 M − 1 . The probe exhibits excellent stability, reversibility, and no interference from other competing anions. Real‐sample applications were also implemented using extracts from apple seeds, flax seeds, and tobacco. Furthermore, AN04 was successfully integrated into test strips and swab kits for analytical on‐site detection. These findings suggest that AN04 is a reliable, affordable, and user‐friendly sensor for rapidly detecting cyanide in water, food, and environmental samples.
Mohan et al. (Sun,) studied this question.