The aim is to explore mechanisms that allow immune cells to control HIV rebound following ART interruption.
Conducted a multiomic analysis of ART-interruption cohorts.
Investigated both cell-extrinsic and cell-intrinsic mechanisms.
Analyzed lymphocyte activity related to HIV control.
Identified key mechanisms that support lymphocyte-mediated control of HIV.
Showed both extrinsic and intrinsic factors influence HIV rebound.
Revealed insights into potential treatment strategies for HIV.
Abstract
Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms
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Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound | Synapse