March 24, 2026Open Access

Coronary Sinus Reduction for REDUCER-I Patients With Refractory Angina and Angiographically Nonobstructive Coronary Artery Disease

Key Result

Coronary sinus Reducer implantation significantly improved symptoms and quality of life in patients with refractory angina and angiographically nonobstructive coronary artery disease.

Key Points

To evaluate the effects of coronary sinus (CS) Reducer implantation on symptoms and quality of life in patients with refractory angina and angiographically nonobstructive coronary artery disease (AngioNOCAD).
Analyzed data from the REDUCER-I registry
Included patients diagnosed with refractory angina
Performed coronary sinus Reducer implantation
Assessed patient-reported outcomes including symptoms and quality of life.
Significant improvements in symptoms reported by patients after implantation
Enhanced quality of life measurements in the study group
Indications of CS Reducer as a possible effective therapy for this population.

Structured PICO

Does CS Reducer implantation improve symptoms and quality of life in patients with refractory angina and angiographically nonobstructive coronary artery disease?

Population

Patients with refractory angina (RA) and angiographically nonobstructive coronary artery disease (AngioNOCAD) in the REDUCER-I registry

Intervention

Coronary Sinus (CS) Reducer implantation

Outcome

Symptoms and quality of lifepatient reported

CS Reducer implantation may be an effective therapy for improving symptoms and quality of life in patients with refractory angina and nonobstructive coronary artery disease.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

In the REDUCER-I registry, patients with RA and AngioNOCAD had significant improvements in their symptoms and quality of life suggesting that CS Reducer implantation may be an effective therapy in these patients.