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March 28, 2026American Journal of Neuroradiology0 citationsOpen Access

Evaluation of the C1-C2 False Localizing Sign in Spontaneous Intracranial Hypotension: Prevalence and Clinical Insights

AMAjay A. MadhavanMayo Clinic PKPeter G. Kranz MKMichelle L. KodetMayo Clinic

Key Points

This research aims to evaluate the prevalence of the C1-C2 false localizing sign in spontaneous intracranial hypotension and its clinical implications.
Evaluated cases of spontaneous intracranial hypotension
Assessed presence of C1-C2 false localizing sign
Analyzed relationship with disease duration and treatment strategies
C1-C2 false localizing sign associated with shorter disease duration
Sign presence may assist in optimal treatment planning for dural tears

Abstract

The C1-C2 false localizing sign is associated with a relatively shorter disease duration. Its presence may be helpful in determining optimal treatment strategies in patients with dural tears.

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