Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis

Key Points

• The article reviews the role of peroxisome proliferator-activated receptors in primary biliary cholangitis and emphasizes the need for isoform-specific investigations.
• Review of existing literature on PPAR agonists and their isoform selectivity.
• Analysis of efficacy and safety profiles of different PPAR agonists.
• Identifies the importance of isoform selectivity in the effectiveness of PPAR agonists.
• Highlights the need for research on isoform-specific mechanisms related to symptom relief.