A reduced radioactive iodine (RAI) dose can achieve successful ablation in dialysis-dependent patients, minimizing systemic radiation exposure and marrow toxicity without compromising efficacy. The timing of the first haemodialysis session after RAI administration is critical to ensure effective thyroidal ablation while minimizing radiation toxicity. There are no standardized guidelines for RAI ablation in end-stage renal disease (ESRD) patients on haemodialysis, necessitating case-by-case multidisciplinary planning.
Alzahmi et al. (Wed,) studied this question.