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September 8, 1998Circulation332 citations

Assessment of Atrioventricular Junction Ablation and VVIR Pacemaker Versus Pharmacological Treatment in Patients With Heart Failure and Chronic Atrial Fibrillation

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MBMichele BrignoleCMC. MenozziLGLorella Gianfranchi

Key Points

  • To evaluate the effectiveness of Abl+Pm treatment compared to pharmacological therapy in heart failure patients with chronic atrial fibrillation.
  • Controlled assessment of symptom management in patients with heart failure and chronic AF

Structured PICO

Does atrioventricular junction ablation and VVIR pacemaker improve symptoms compared to pharmacological treatment in patients with heart failure and chronic atrial fibrillation?

P
Population
Patients with heart failure and chronic atrial fibrillation
I
Intervention
Atrioventricular junction ablation and VVIR pacemaker
C
Comparator
Pharmacological treatment

AV junction ablation with VVIR pacemaker implantation improves symptom control compared to medical therapy in patients with heart failure and chronic AF, though it does not modify cardiac performance.

Abstract

In patients with heart failure and chronic AF, Abl+Pm treatment is effective and superior to drug therapy in controlling symptoms, although its efficacy appears to be less than that observed in uncontrolled studies because some improvement can also be expected in medically treated patients. Cardiac performance is not modified by the treatment.

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Cite This Study

Brignole et al. (1998) studied this question.

synapsesocial.com/papers/69d56b3575589c71d767c953https://doi.org/10.1161/01.cir.98.10.953
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