Does left bundle branch area pacing or His bundle pacing improve LVEF and QRS duration compared to biventricular pacing in patients requiring cardiac resynchronization therapy?
Conduction system pacing (LBBAP and HBP) provides superior electrical and echocardiographic resynchronization compared to traditional biventricular pacing, with LBBAP offering more favorable pacing thresholds than HBP.
The NMA first found that LBBAP and HBP resulted in a greater LVEF improvement and a narrower QRS duration compared with BVP. Additionally, LBBAP resulted in similar clinical outcomes but with lower pacing thresholds, and may therefore offer advantages than does HBP for CRT.
Hua et al. (Tue,) studied this question.