The diagnosis of Ehlers-Danlos syndrome type IV should be considered in young patients presenting with uterine, arterial, or visceral rupture.
Although most affected patients survive the first and second major complications, Ehlers-Danlos syndrome type IV results in premature death. The diagnosis should be considered in young people who come to medical attention because of uterine rupture during pregnancy or arterial or visceral rupture.
Pepin et al. (Thu,) studied this question.