October 28, 2015

Selective Hydrogenolysis of Arenols with Hydrosilanes by Nickel Catalysis

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Abstract

Nickel-catalyzed hydrogenolysis of arenols has been developed through the use of hydrosilane as a reductant. Sterically demanding N-heterocyclic carbene (NHC) ligands are crucial for the reaction. The present protocol allows selective cleavage of Ar–O bonds of arenols over aryl and benzyl ethers.

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Ohgi et al. (Wed,) studied this question.

synapsesocial.com/papers/69d990f5c7f0c3ae80a3de28 https://doi.org/https://doi.org/10.1246/cl.150807

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