May 1, 2013Open Access

Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies

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Abstract

Late-life depression is associated with an increased risk for all-cause dementia, vascular dementia and Alzheimer's disease. The present results suggest that it will be valuable to design clinical trials to investigate the effect of late-life depression prevention on risk of dementia, in particular vascular dementia and Alzheimer's disease.

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Diniz et al. (Wed,) studied this question.

synapsesocial.com/papers/69d9ad3ce6ab964fb0836150 https://doi.org/https://doi.org/10.1192/bjp.bp.112.118307

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1Early Intervention to Reduce the Global Health and Economic Burden of Major Depression in Older Adults2012 · 164 citations
2Medical comorbidity and late life depression: what is known and what are the unmet needs?2002 · 108 citations
3Vascular Dementia2000 · 334 citations
4The Influence of Vascular Disease on Cognitive Performance in the Preclinical and Early Phases of Alzheimer’s Disease2010 · 28 citations
5Changes in Cognitive Functioning Following Treatment of Late-Life Depression2000 · 363 citations

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