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July 26, 2010BMJ2,359 citationsOpen Access

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis

SDStéphanie DebetteHMHugh S. Markus

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Abstract

White matter hyperintensities predict an increased risk of stroke, dementia, and death. Therefore white matter hyperintensities indicate an increased risk of cerebrovascular events when identified as part of diagnostic investigations, and support their use as an intermediate marker in a research setting. Their discovery should prompt detailed screening for risk factors of stroke and dementia.

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Debette et al. (2010) studied this question.

synapsesocial.com/papers/69dad27278a3e0e28868479ehttps://doi.org/10.1136/bmj.c3666
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