Foetal Development and Placental Health in Response to Apical Periodontitis Induced in Pregnant Wistar Rats

Key Points

• To investigate how apical periodontitis impacts placental health and fetal development in pregnant Wistar rats.
• Induced apical periodontitis in multiple maternal teeth of pregnant Wistar rats.
• Monitored changes in placental health and fetal development as the number of affected teeth increased.
• Conducted comparative assessments to determine the severity of effects.
• More pronounced alterations were observed in placental health with an increasing number of maternal teeth affected by apical periodontitis.
• Negative effects on fetal development correlated with the severity of dental health issues during pregnancy.