January 30, 2006

Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis

MLMaria LeandroUniversity College Hospital GCGeraldine CambridgeUniversity College London MEMichael R. EhrensteinUniversity College Hospital

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Abstract

Rituximab induced a profound depletion of all peripheral blood B cell populations in patients with RA. Repopulation occurred mainly with naive mature and immature B cells. Patients whose RA relapsed on return of B cells tended to show repopulation with higher numbers of memory B cells.

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Leandro et al. (Mon,) studied this question.

synapsesocial.com/papers/69dbaea450e1971baba3c365 https://doi.org/https://doi.org/10.1002/art.21617

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