July 19, 2017Open Access

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa

Key Points

Key points are not available for this paper at this time.

Abstract

Among HIV-infected patients with advanced immunosuppression, enhanced antimicrobial prophylaxis combined with ART resulted in reduced rates of death at both 24 weeks and 48 weeks without compromising viral suppression or increasing toxic effects. (Funded by the Medical Research Council and others; REALITY Current Controlled Trials number, ISRCTN43622374 .).

Read Full Paperexternally

Bookmark

View Full Paper

Cite This Study

Hakim et al. (Wed,) studied this question.

synapsesocial.com/papers/69dc91b3a5c75be4cfe5307d https://doi.org/https://doi.org/10.1056/nejmoa1615822

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Rifampin and Pyrazinamide vs Isoniazid for Prevention of Tuberculosis in HIV-Infected Persons<SUBTITLE>An International Randomized Trial</SUBTITLE>2000 · 265 citations
2Country-Level Cost-Effectiveness Thresholds: Initial Estimates and the Need for Further Research2016 · 920 citations
3Assessment of Second-Line Antiretroviral Regimens for HIV Therapy in Africa2014 · 204 citations
4Early Mortality in Adults Initiating Antiretroviral Therapy (ART) in Low- and Middle-Income Countries (LMIC): A Systematic Review and Meta-Analysis2011 · 259 citations
5Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases2010 · 275 citations

Bookmark

View Full Paper