June 12, 2019Open Access

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis

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Abstract

Routine microbiologic testing is often insufficient to detect all neuroinvasive pathogens. In this study, metagenomic NGS of CSF obtained from patients with meningitis or encephalitis improved diagnosis of neurologic infections and provided actionable information in some cases. (Funded by the National Institutes of Health and others; PDAID ClinicalTrials.gov number, NCT02910037.).

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Wilson et al. (Wed,) studied this question.

synapsesocial.com/papers/69dd4abd8557d5ab8f40ca85 https://doi.org/https://doi.org/10.1056/nejmoa1803396

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