January 31, 2019Open Access

CYT997(Lexibulin) induces apoptosis and autophagy through the activation of mutually reinforced ER stress and ROS in osteosarcoma

ZWZongyi WangUtrecht University FYFei YinUnion Hospital JXJing XuShanghai Sixth People's Hospital

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Abstract

This study suggests that CYT997 induces apoptosis and autophagy in OS cells by triggering mutually enhanced ER stress and ROS and may thus be a promising agent against OS.

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Wang et al. (Thu,) studied this question.

synapsesocial.com/papers/69dd6f189a26440201100e8d https://doi.org/https://doi.org/10.1186/s13046-019-1047-9

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