What question did this study set out to answer?

To investigate the timing of fibrous coverage following left atrial appendage occlusion.

April 14, 2026Open Access

Early Healing After Left Atrial Appendage Occlusion Confirmed by Surgical Explantation

KHKaoru HasegawaTohoku Medical and Pharmaceutical University MYMinoru YambeTohoku Medical and Pharmaceutical University Hospital KKKazushi KinebuchiTohoku Medical and Pharmaceutical University

Key Result

Left atrial appendage occlusion can result in early fibrous coverage within 3 months, as demonstrated by surgical explantation.

Key Points

To investigate the timing of fibrous coverage following left atrial appendage occlusion.
Observation of the healing process after LAA occlusion
Surgical explantation of occluded appendage for assessment
Fibrous coverage observed within 3 months post-occlusion
Demonstration of early healing response in cardiac tissue

Structured PICO

Does left atrial appendage occlusion result in early fibrous coverage within 3 months?

Population

Patients undergoing left atrial appendage (LAA) occlusion

Intervention

Left atrial appendage (LAA) occlusion

Outcome

Early fibrous coverage assessed by surgical explantationsurrogate

Surgical explantation confirms that fibrous coverage of LAA occlusion devices can occur as early as 3 months post-procedure.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Early fibrous coverage after LAA occlusion may occur within 3 months, as demonstrated by surgical explantation.

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Cite This Study

Hasegawa et al. (Wed,) reported a other. Left atrial appendage occlusion can result in early fibrous coverage within 3 months, as demonstrated by surgical explantation.

synapsesocial.com/papers/69ddd8eee195c95cdefd662c https://doi.org/https://doi.org/10.1016/j.jaccas.2026.107859