Is there an independent and continuous relationship between systolic blood pressure and adverse LV remodeling in healthy normotensive adults?
Adverse LV remodeling, characterized by concentric septal and eccentric lateral wall hypertrophy, begins in healthy normotensive adults and correlates continuously with systolic blood pressure, challenging conventional classifications.
These findings show that the precursors of the hypertensive heart phenotype can be traced to healthy normotensive adults and that an independent and continuous relationship exists between adverse LV remodeling and SBP in a low-risk population. These adaptations show distinct regional variations with concentric hypertrophy of the septum and eccentric hypertrophy of the lateral wall, which challenge conventional classifications of LV remodeling.
Marvao et al. (Thu,) studied this question.
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