What question did this study set out to answer?

The aim is to establish and validate a prognostic signature based on glycolysis-related lncRNAs in osteosarcoma.

April 15, 2026Discover Oncology0 citationsOpen Access

Construction and validation of a novel prognostic signature that correlates with immune infiltration based on glycolysis related lncRNAs in osteosarcoma

SMShiwei MaMianyang Central Hospital LYLiling YangMianyang Central Hospital HLHongyuan LiuChinese Academy of Medical Sciences & Peking Union Medical College

Key Points

The aim is to establish and validate a prognostic signature based on glycolysis-related lncRNAs in osteosarcoma.
Constructed a prognostic model using glycolysis-related lncRNAs
Validated the model's accuracy and reliability
Analyzed correlations with immune cell infiltration
Identified significant glycolysis-related lncRNAs associated with patient prognosis
Model provides a robust tool for clinical risk evaluation
Correlation found between the model and immune infiltration in osteosarcoma

Abstract

This study revealed the prognostic value of glycolytic-associated lncRNAs in osteosarcoma. The novel glycolysis-associated lncRNA-based model may offer new insights into prognostic evaluation and clinical risk decision for patients with osteosarcoma.

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