Longitudinal Surveillance of Gastric Polyposis in Familial Adenomatous Polyposis: Incidence, Progression, and Endoscopic Outcomes

Key Points

• The study aims to examine the incidence and progression of gastric polyposis in patients with familial adenomatous polyposis (FAP).
• Conducted a longitudinal examination of gastric polyposis in individuals with FAP.
• Monitored progression of fundic gland polyposis and its association with gastric neoplasia.
• Analyzed endoscopic outcomes related to gastric surveillance strategies.
• Identified a high incidence of fundic gland polyposis in FAP patients.
• Found a significant association between fundic gland polyposis and proximal gastric neoplasia risk.
• Demonstrated the necessity of phenotype-driven gastric surveillance strategies to prevent progression.