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This research evaluates the presence of sTREM2 in cerebrospinal fluid, serum, and plasma to determine their relationship.

April 15, 2026Open Access

Evaluation of Soluble Triggering Receptor Expressed on Myeloid Cells 2 ( sTREM2 ) in Cerebrospinal Fluid, Serum, and Plasma Using the Fully Automated Lumipulse Platform

Key Points

This research evaluates the presence of sTREM2 in cerebrospinal fluid, serum, and plasma to determine their relationship.
Analyzed sTREM2 levels in cerebrospinal fluid, serum, and plasma samples.
Utilized the fully automated Lumipulse platform for measurement.
Compared the agreement between sTREM2 levels in different body fluids.
sTREM2 levels in cerebrospinal fluid and blood show distinct biological processes.
Serum and plasma sTREM2 levels are closely related but not interchangeable.
Limited overall agreement in sTREM2 levels between cerebrospinal fluid and blood.

Abstract

CSF and blood sTREM2 capture partly distinct biological processes and show limited overall agreement. While serum and plasma sTREM2 are closely related, they are not interchangeable.

Evaluation of Soluble Triggering Receptor Expressed on Myeloid Cells 2 ( sTREM2 ) in Cerebrospinal Fluid, Serum, and Plasma Using the Fully Automated Lumipulse Platform

Key Points

Abstract

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