Assessment of exonic polymorphism of IDH2 , KRAS1 , TP53 , and BRAF2 using PCR-RFLP in hepatocellular carcinoma: a case–control study from Arunachal Pradesh and Sikkim | Synapse
April 16, 2026
Assessment of exonic polymorphism of IDH2 , KRAS1 , TP53 , and BRAF2 using PCR-RFLP in hepatocellular carcinoma: a case–control study from Arunachal Pradesh and Sikkim
Key Points
This research aims to evaluate the genetic polymorphisms of specific genes in hepatocellular carcinoma.
Conducted a case-control study design.
Utilized PCR-RFLP to assess genetic variations.
Focused on genes IDH2, KRAS1, TP53, and BRAF2.
Sampled participants from Arunachal Pradesh and Sikkim.
Identified significant genetic variations linked to hepatocellular carcinoma.
Suggested therapeutic possibilities based on findings.
Abstract
Our findings in the genetic landscape highlight the complexity of hepatocarcinogenesis but also point to potential therapeutic exploitation.