Metabolomics-based study of potential biomarkers and metabolic pathways in sepsis-associated acute kidney injury

Key Points

• The central aim is to identify metabolic biomarkers and pathways associated with sepsis-related acute kidney injury.
• Conducted a metabolomics analysis to identify metabolic changes in sepsis-associated acute kidney injury.
• Performed qualitative and quantitative assessments of metabolites in patients with SA-AKI.
• Analyzed metabolic pathways to uncover potential targets for intervention.
• Identified several potential biomarkers associated with sepsis-related acute kidney injury.
• Revealed alterations in specific metabolic pathways linked to SA-AKI.
• Demonstrated that targeted metabolic profiling can aid in the understanding of SA-AKI.