Background: Patients undergoing hematopoietic stem cell transplantation (HSCT) are at high risk for physical inactivity and malnutrition. International guidelines recommend combining physical activity and nutrition support to improve treatment outcomes. However, these recommendations are not yet implemented in clinical care in Sweden. Objective: The aim of this study was to investigate the feasibility and acceptability of a nurse-led intervention supporting physical activity and nutritional intake in patients undergoing HSCT. Methods: Twenty adults undergoing HSCT participated in a nurse-led intervention supporting physical activity and nutrition, including a dietitian consultation and behavior change strategies (goal setting, self-monitoring, and follow-ups). Feasibility and acceptability were assessed via recruitment and consent rates, adherence to nutrition and activity components, and interviews to capture patients’ experiences. Results: Of 52 eligible patients, 27 were approached, 22 consented (81%), and 20 completed the intervention (median age 57.5 years). Adherence was high, with all participants setting physical activity goals, 95% completing diaries, a mean activity of 57.5 minutes/day, and 75% achieving target energy intake. Qualitative analysis highlighted both facilitators and barriers to engagement. Conclusions: A nurse-led intervention supporting physical activity and nutrition for patients undergoing HSCT is feasible and acceptable. Starting the intervention pretransplant appears important for establishing habits and preparing patients for treatment. Implications for Practice: Several components of this nurse-led intervention could be implemented in standard HSCT care without major organizational changes. Structured nutritional follow-up, daily physical activity encouragement, individualized goal setting visualized at the bedside, and follow-up by dedicated nurses align with existing nursing responsibilities and appear feasible for immediate adoption.
Vejby et al. (Wed,) studied this question.