Laser-assisted vs. conventional daylight photodynamic therapies for actinic keratosis: a two-year randomized evaluator-blinded half-side comparative trial

Key Points

• This research aims to compare the effectiveness of laser-assisted daylight photodynamic therapy versus conventional daylight photodynamic therapy for treating actinic keratosis.
• Conducted a randomized evaluator-blinded trial
• Participants received treatment on half of their affected areas
• Follow-up assessments took place over two years
• Laser-assisted therapy showed a higher long-term sustained clearance rate
• Demonstrated superior effectiveness compared to daylight therapy alone