Study of the possibility of isolating atazanavir from biological fluids for the purpose of chemical-toxicological analysis

Key Points

• The aim is to establish effective methods for isolating atazanavir from biological fluids for toxicological analysis.
• Developed liquid-liquid extraction techniques for urine, saliva, and blood plasma.
• Employed thin-layer chromatography for identification of atazanavir.
• Used UV spectrophotometry and high-performance liquid chromatography for quantification of the substance.
• Identified optimal extraction conditions for atazanavir.
• Successfully quantified atazanavir in various biological fluids using the developed methods.