Mediterranean and western diets differentially modulate cellular aging, oxidative stress, and inflammation in rats: a randomized control trial

Key Points

• The research aims to examine how different diets influence cellular aging and stress markers in rats.
• Conducted a randomized control trial comparing Mediterranean and Western diets in rats.
• Measured markers of oxidative stress, inflammation, and cellular aging.
• Assessed telomere integrity and hippocampal cell survival.
• The Mediterranean diet preserved telomere integrity and enhanced hippocampal cell survival.
• The Western diet accelerated markers of molecular aging.
• Dietary composition significantly modulated oxidative stress and inflammation levels.