Association between dynamic trajectories of serum tumor markers and survival outcomes in patients with extensive-stage small cell lung cancer: a retrospective cohort study

Key Points

• This research aims to evaluate how changes in serum tumor markers relate to survival outcomes in extensive-stage small cell lung cancer.
• Performed a retrospective cohort study
• Monitored serum levels of NSE, CEA, and CYFRA21-1 over time
• Analyzed the correlation between marker dynamics and survival outcomes
• Dynamic monitoring of tumor markers correlates with improved prognostic predictions
• Higher levels of NSE, CEA, and CYFRA21-1 are associated with poorer survival outcomes
• Patients with regular monitoring show better management and potential survival benefits