Background: Post-tuberculosis lung disease (PTLD) may develop after tuberculosis treatment due to ongoing airway inflammation, potentially leading to muscle loss and malnutrition. Several studies have shown that vitamin D, a regulator of pro-inflammatory mediators, can influence this process. However, the association between vitamin D intake and nutritional status indicators, such as mid-upper arm circumference (MUAC) and calf circumference, remains understudied in PTLD patients. Objective: To assess the association of vitamin D intake with MUAC and calf circumference in PTLD patients. Methods: This cross-sectional study was conducted at Persahabatan Hospital, Jakarta, Indonesia, from October 2024 to April 2025, involving 87 patients with PTLD. Vitamin D intake was assessed using the semi-quantitative food frequency questionnaire, while MUAC and calf circumference were measured according to the FANTA III-recommended measurement procedures. Results: The results showed that the average age of the participants was 63 years, with the majority being male (79.3%). The average vitamin D intake was 2.2 μg/day, which was below the recommended dietary allowance. The average MUAC was 26 cm, and the calf circumference was 30.9 cm. The results showed that there was a significant negative correlation between vitamin D intake and MUAC ( r = −0.213; P = 0.048), but no significant correlation with calf circumference ( r = −0.093; P = 0.390). Conclusion: A significant negative correlation was found between vitamin D intake and MUAC in PTLD patients, while no significant correlation was observed with calf circumference. Further studies are required to determine the impact of vitamin D on the fat-free mass parameters.
Nurwidya et al. (Sun,) studied this question.