Phase 2 trial of exercise and low‐dose ibuprofen for cancer‐related cognitive impairment in patients receiving chemotherapy | Synapse
April 22, 2026Open Access
Phase 2 trial of exercise and low‐dose ibuprofen for cancer‐related cognitive impairment in patients receiving chemotherapy
Key Points
This trial aimed to assess the impact of exercise and low-dose ibuprofen on cognitive impairment in cancer patients undergoing chemotherapy.
Conducted a Phase 2 trial with a focus on cognitive function assessments post-intervention.
Participants received low-dose ibuprofen and engaged in exercise regimens.
Exercise and ibuprofen showed improvements in some areas of cognitive function.
Improvements were not consistent across all cognitive measures.
Abstract
Exercise and low-dose ibuprofen improved some domains of cognitive function, although effects were not observed across all measures. Phase 3 trials are needed.