Sexually Dimorphic Impacts of Early Life BCAAs Supplementation on Metabolic Dysfunctions in Adult Mice

Key Points

• This research investigates how early life BCAA supplementation affects metabolic health differently in male and female adult mice.
• Supplementation of individual BCAAs during the lactation period in a mouse model.
• Assessment of metabolic functions in adult mice following early exposure to BCAAs.
• Male mice showed pronounced metabolic dysfunction due to excessive BCAA exposure during lactation.
• Distinct differences were observed in metabolic outcomes between male and female adult mice.

Abstract