What question did this study set out to answer?

To evaluate capillary β-hydroxybutyrate (β-OHB) levels in diagnosing diabetic ketoacidosis (DKA).

April 25, 2026Open Access

A review of capillary β‐hydroxybutyrate cut‐off levels for the exclusion and identification of diabetic ketoacidosis

Key Points

To evaluate capillary β-hydroxybutyrate (β-OHB) levels in diagnosing diabetic ketoacidosis (DKA).
Reviewed existing literature on β-OHB levels relevant to DKA diagnosis.
Assessed cut-off levels for excluding and identifying DKA.
Capillary β-OHB threshold of <1.5 mmol/L may exclude DKA.
A level >3.0 mmol/L showed high sensitivity and specificity for DKA detection.

Abstract

Capillary testing can reliably detect β-OHB levels within the DKA diagnostic threshold. While a capillary β-OHB threshold of 3.0 mmol/L showed high sensitivity and specificity in detecting DKA. Future studies are needed to validate proposed cut-offs and examine the utility of capillary β-OHB testing in prehospital settings.

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Cite This Study

Tran et al. (Thu,) studied this question.

synapsesocial.com/papers/69ec5b2388ba6daa22dacb83 https://doi.org/https://doi.org/10.1111/jdi.70317

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