July 1, 1975Circulation

All surviving patients described symptomatic improvement, and among 52 patients with preoperative resting obstruction studied postoperatively, 47 had no resting gradient and 5 had a gradient <25 mm Hg, with 6 operative deaths (7%).

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Why the study?

Does left ventriculomyotomy and myectomy improve symptoms and reduce outflow gradients in severely incapacitated patients with idiopathic hypertrophic subaortic stenosis?

Population

83 patients with idiopathic hypertrophic subaortic stenosis who were severely incapacitated, with documented…

Design

Case_series

Follow-up

up to 14 years

Authors

AMAndrew G. Morrow BRB. A. Reitz SEStephen E. Epstein

Discussion

Member takes

Overview

Supports myectomy for refractory obstructive HCM symptoms; leaves open need for modern randomized validation of safety and durability.

Structured PICO

Does left ventriculomyotomy and myectomy improve symptoms and reduce outflow gradients in severely incapacitated patients with idiopathic hypertrophic subaortic stenosis?

Population

83 patients with idiopathic hypertrophic subaortic stenosis (IHSS) who were severely incapacitated (58 in Class III and 24 in Class IV), with documented severe obstruction at rest (n=70, average gradient 96 mm Hg) or provocable obstruction (n=13).

Intervention

Left ventriculomyotomy and myectomy (resection of a vertical bar of muscle between parallel myotomy incisions via aortotomy).

Outcome

Symptomatic improvement and relief of left ventricular outflow tract obstruction (gradient reduction).

Left ventriculomyotomy and myectomy provides long-lasting symptomatic and hemodynamic improvement in severely incapacitated patients with idiopathic hypertrophic subaortic stenosis.

Cite This Study

Morrow et al. (1975) studied this question.

synapsesocial.com/papers/69eff9e14f6a06657c21dd9a https://doi.org/10.1161/01.cir.52.1.88

View Full Paper

Ask AI

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July 1, 1975Circulation

All surviving patients described symptomatic improvement, and among 52 patients with preoperative resting obstruction studied postoperatively, 47 had no resting gradient and 5 had a gradient <25 mm Hg, with 6 operative deaths (7%).

View Full Paper

Ask AI

Bookmark

Why the study?

Does left ventriculomyotomy and myectomy improve symptoms and reduce outflow gradients in severely incapacitated patients with idiopathic hypertrophic subaortic stenosis?

Population

83 patients with idiopathic hypertrophic subaortic stenosis who were severely incapacitated, with documented…

Design

Case_series

Follow-up

up to 14 years

Authors

AMAndrew G. Morrow BRB. A. Reitz SEStephen E. Epstein

Discussion

Member takes

Overview

Supports myectomy for refractory obstructive HCM symptoms; leaves open need for modern randomized validation of safety and durability.

Structured PICO

Does left ventriculomyotomy and myectomy improve symptoms and reduce outflow gradients in severely incapacitated patients with idiopathic hypertrophic subaortic stenosis?

Population

Intervention

Left ventriculomyotomy and myectomy (resection of a vertical bar of muscle between parallel myotomy incisions via aortotomy).

Outcome

Symptomatic improvement and relief of left ventricular outflow tract obstruction (gradient reduction).

Left ventriculomyotomy and myectomy provides long-lasting symptomatic and hemodynamic improvement in severely incapacitated patients with idiopathic hypertrophic subaortic stenosis.

Cite This Study

Morrow et al. (1975) studied this question.

synapsesocial.com/papers/69eff9e14f6a06657c21dd9a https://doi.org/10.1161/01.cir.52.1.88

View Full Paper

Ask AI

Bookmark