April 20, 2016Open Access
Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis
Structured PICO
Do β blockers reduce the risk of death and admission to hospital in patients with HFrEF in sinus rhythm irrespective of age or sex?
P
Population
Patients with heart failure with reduced ejection fraction (HFrEF) in sinus rhythm
I
Intervention
β blockers
O
Outcome
Death and admission to hospitalhard clinical
Beta blockers are effective in reducing death and hospital admission in HFrEF patients in sinus rhythm, regardless of age or sex.
Abstract
Irrespective of age or sex, patients with HFrEF in sinus rhythm should receive β blockers to reduce the risk of death and admission to hospital.Registration PROSPERO CRD42014010012; Clinicaltrials.gov NCT00832442.
Cite This Study
Kotecha et al. (Wed,) studied this question.