Does cardiovascular MR imaging identify myocardial crypts as a marker for early evaluation of HCM families?
Myocardial crypts detected by cardiovascular MR may serve as a novel imaging marker to identify HCM family members who should undergo diagnostic genetic testing.
LV myocardial crypts represent a distinctive morphological expression of HCM, occurring with different frequency in HCM patients with or without LV hypertrophy. Crypts are a novel cardiovascular MR imaging marker, which may identify individual HCM family members who should also be considered for diagnostic genetic testing. These data support an expanded role for cardiovascular MR in early evaluation of HCM families.
Maron et al. (Sun,) studied this question.