Aim: This study aimed to investigate the associations of sleep duration, diet quality, and body fat classification with IgG levels, biochemical parameters, and anthropometric measurements in volunteers who received two doses of the COVID-19 vaccine.Method: A total of 61 volunteers participated in the study. Biomarkers, anthropometric measurements, physical activity, sleep duration, and serum IgG levels were assessed. Dietary Quality Index-2015 (DQI-2015) and nutrient intake were calculated using the CeviCal program based on food frequency data. Results: Individuals with short sleep duration had significantly higher fasting blood sugar levels compared to those with normal sleep duration (p0.05). Individuals with long sleep duration had higher serum IgG levels compared to those with normal sleep duration (p=0.029). LDL cholesterol levels were lower in individuals who consumed alcohol, while T3 levels were lower in smokers (p0.05). Total cholesterol, non-HDL cholesterol, and waist circumference values were higher in individuals with poor diet quality (p0.05). Total cholesterol and triglyceride levels were found to be higher in obese individuals (p0.05). The increase in IgG levels was found to be associated with an increase in fasting serum glucose levels, and a moderate positive correlation was found between these parameters (p0.001, r=0.445). IgG levels were significantly lower in individuals with high daily vitamin C intake (p=0.037). 25(OH)D levels were lower in individuals with active physical activity levels compared to inactive individuals (p0.05).Conclusion: Short sleep duration, poor diet quality, and obesity have been associated with adverse changes in glucose, lipid profile, and anthropometric measurements. Long sleep duration has been associated with higher IgG levels, while high vitamin C intake has been associated with lower IgG levels. Additionally, increased IgG levels have been associated with higher glucose levels. Larger sample studies are needed to confirm these findings.
Fatih Cesur (Sat,) studied this question.