Background: Daivavyapashraya Chikitsa, one of the three fundamental therapeutic modalities described in classical Ayurveda, encompasses spiritual and ritualistic interventions intended to correct subtle etiological factors influencing health. Among these, Homa Therapy (Agnihotra/Yajna) represents a ritual fire-based intervention traditionally believed to purify the environment and consciousness. Dhatusarata refers to the qualitative excellence of body tissues (Dhatus), while Sattva Sarata denotes psychological purity and mental resilience. Despite classical assertions linking spiritual practices to enhancement of tissue quality and psychological stability, empirical evaluation remains limited. Daivavyapashraya Chikitsa (spiritual therapy) is a fundamental yet under-researched Ayurvedic modality intended for diseases with subtle etiologies (Adrishta Hetu). Objective: To evaluate Homa Therapy as a psychosomatic intervention for optimizing Dhatusarata (tissue excellence) by modulating Sattva Sarata (mental resilience). Methods: A prospective, interventional, single-arm clinical study was conducted for 12 weeks. Forty participants (n=40) aged 25–50 years with moderate Sattva Sarata were enrolled. Baseline assessment included Dhatusarata scoring based on classical criteria and validated psychometric tools for mental well-being. Participants underwent supervised Homa Therapy sessions thrice weekly. Pre and post-intervention comparisons were analyzed using paired t-tests and correlation statistics. Results: Significant improvement was observed in Sattva Sarata scores (p < 0.001). Secondary outcomes demonstrated measurable enhancement in Rasasara and Raktasara parameters, improved sleep quality, reduced perceived stress scores, and improved HRV indices. Positive correlation was observed between increased Sattva Sarata and Dhatusarata enhancement (r = 0.62) with Rasa and Rakta Sarata improvements. Conclusion: Homa Therapy acts as a potent "Psychosomatic Catalyst," validating the classical link between a pure mind (Sattva) and high-quality tissues (Dhatus).
Ital et al. (Sun,) studied this question.