Ameliorating effects of stevia extract combined with green-synthesized silver nanoparticles coated with soy soluble polysaccharide on diabetic wounds in the rat model

Key Points

• This study aims to assess the efficacy of stevia extract combined with green-synthesized silver nanoparticles in enhancing diabetic wound healing in rats.
• Evaluated the impact of stevia extract and silver nanoparticles on diabetic wounds in a rat model.
• Utilized a green synthesis method for producing silver nanoparticles to reduce cytotoxicity.
• Employed various assessments for wound healing progression.
• Significant improvement in wound healing observed in the combined treatment group compared to controls, with a faster healing rate.
• Reduction in signs of cytotoxicity associated with the use of green-synthesized silver nanoparticles.
• Demonstrated effective closure rates of diabetic wounds attributed to the combined therapy.