Stimuli-responsive nanoplatforms for central nervous system disorders: integrating delivery, modulation, and imaging

Key Points

• The research aims to explore the effectiveness of stimuli-responsive nanoplatforms in treating central nervous system disorders by facilitating drug delivery and neuromodulation.
• Integration of endogenous cues and external fields for BBB-crossing delivery.
• Application of nanoplatforms for imaging-guided therapies.
• Assessment of neuromodulation capabilities in adaptive treatment strategies.
• Demonstrated successful crossing of the blood-brain barrier by nanoplatforms.
• Showed enhanced neuromodulation effects in targeted CNS regions.
• Improved imaging accuracy leading to more effective therapy guidance.