BACKGROUND: leaves on SCI, evaluating its impact on oxidative stress, inflammation, and both structural and functional recovery. MATERIALS AND METHODS: (150 mg/kg of M.P extract injected intraperitoneally for 21 days). Motor function was assessed using the Basso, Beattie, and Bresnahan (BBB) scale throughout the study period. At 21 days post-injury, we measured the activity of antioxidant enzymes (superoxide dismutase SOD, catalase CAT, glutathione peroxidase GPx, total antioxidant capacity TAC), the oxidative stress marker malondialdehyde (MDA), and inflammatory cytokines (TNF-α, IL-1β, IL-6, IL-18), alongside nuclear factor kappa B (NF-κB). Histological analyses were performed using hematoxylin and eosin (H&E) and cresyl violet staining to evaluate neuronal damage and tissue density. RESULTS: group, as evidenced by higher BBB scores compared to the untreated SCI group. CONCLUSION: in the treatment of SCI.
Tajik et al. (Wed,) studied this question.