What is the clinical evidence from this study?

Study design: Editorial. Population: Cardiovascular disease. Intervention: Myocardial Work (MW) vs. Global Longitudinal Strain (GLS).

February 28, 2026Open Access

What Does Myocardial Work Offer Beyond Strain?

Key Result

Myocardial work provides incremental diagnostic and prognostic information beyond global longitudinal strain by integrating longitudinal myocardial deformation with systemic arterial pressure.

Structured PICO

Does myocardial work assessment improve diagnostic and prognostic evaluation compared to global longitudinal strain in patients with cardiac disease?

Intervention

Myocardial Work (MW) assessment using echocardiography

Comparator

Global Longitudinal Strain (GLS) alone

Outcome

Diagnostic and prognostic value in various clinical scenarios (Coronary Artery Disease, STEMI, Aortic Valve Stenosis, Cardiac Resynchronization Therapy)surrogate

Myocardial work is a valuable complementary echocardiographic tool to global longitudinal strain, offering refined diagnostic and prognostic insights by accounting for loading conditions.

Limitations

Measurement depends on adequate image quality for reliable speckle tracking
Relies on noninvasive estimation of systemic blood pressure, requiring careful consideration in specific clinical contexts
Analysis is currently restricted to a single proprietary software platform
Available evidence originates from a limited number of centers with relatively small sample sizes and short follow-up periods

Connected Papers

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Discussion

Journals

ARQUIVOS BRASILEIROS DE CARDIOLOGIA - IMAGEM CARDIOVASCULAR

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Cite This Study

Santos et al. (Wed,) conducted a editorial in Cardiovascular disease. Myocardial Work (MW) vs. Global Longitudinal Strain (GLS) was evaluated. Myocardial work provides incremental diagnostic and prognostic information beyond global longitudinal strain by integrating longitudinal myocardial deformation with systemic arterial pressure.

synapsesocial.com/papers/6a025aa69cddff7633412e3c https://doi.org/https://doi.org/10.36660/abcimg.20250103i